Journal of Lipid Research, Vol. 1, 97-101, October 1959
Copyright © 1959 by Lipid Research, Inc.
The liberation of lipoprotein lipase by heparin from adipose tissue incubated in vitro
Amelia Cherkes and Robert S. Gordon Jr.
Laboratory of Metabolism, National Heart Institute, Bethesda 14, Maryland
Epididymal fat tissues of rats, incubated in vitro in the presence of heparin, have been found to release lipoprotein lipase into the medium. This release occurs rapidly and shows little dependence upon the composition of the medium. The tissues of carbohydrate-fed rats are more active with respect to lipoprotein lipase liberation than those of fasted animals.
Submitted on June 25, 1959