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Journal of Lipid Research, Vol. 10, 193-196, March 1969
Copyright © 1969 by Lipid Research, Inc.

Short-term effect of nicotinic acid on plasma level and turnover of free fatty acids in sheep and man

E. R. Nye and Hilaire Buchanan

Department of Medicine, University of Otago Medical School, Dunedin, New Zealand

The effects of nicotinic acid on plasma free fatty acid levels and turnover and on plasma glycerol levels were studied in the first few hours after administration to man and the sheep. In both species a fall in all parameters studied was followed by a rise above basal level, interpreted as due to an increase in lipolysis above resting level. The significance of the findings is discussed.

Supplementary key words glycerol • rebound effect

Submitted on June 10, 1968
Accepted on October 3, 1968

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