J. Lipid Res.
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Journal of Lipid Research, Vol. 10, 344-345, May 1969
Copyright © 1969 by Lipid Research, Inc.

Synthesis of fatty acyl CoA and other thiol esters using N-hydroxysuccinimide esters of fatty acids

Adhid Al-Arif and Melvin Blecher

Department of Biochemistry, Schools of Medicine and Dentistry, Georgetown University, Washington, D. C. 20007

N-Hydroxysuccinimide esters of long-chain fatty acids have been used to synthesize the CoA and thioglycolic acid thiol esters of palmitic and 3-ketopalmitic acids in high yield and with a minimum of untoward side reactions.

Supplementary key words palmitoyl-S-CoA • 3-ketopalmitoyl-S-thioglycolate • ketal of 3-ketopalmitic acid

Submitted on December 11, 1968
Accepted on February 20, 1969


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