J. Lipid Res. Acyl Labeled PIP's available August 1, 2008
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Journal of Lipid Research, Vol. 10, 535-538, September 1969
Copyright © 1969 by Lipid Research, Inc.

Correlation between percentage of palmitic acid in adipose tissue and serum cholesterol level in patients with multiple sclerosis

William Insull Jr. , Harold B. Houser , and Arthur S. Littell

Departments of Medicine, Preventive Medicine and Biometry, Case Western Reserve University, Cleveland, Ohio 44106; and Highland View Hospital, Cleveland, Ohio 44122

To investigate mechanisms controlling the concentration of serum cholesterol we studied its relationship to the proportions of fatty acids in the lipids of adipose tissue of patients with multiple sclerosis. In 26 men the serum cholesterol concentration had a significant multiple linear regression on the proportion of palmitic, palmitoleic, and grouped longer-chain acids in adipose tissues. In 29 women the serum cholesterol had a significant regression on the proportion of palmitic acid and age. Whether these observations would hold for normal people must be determined in future studies.

Supplementary key words palmitoleic acid • multiple regression

Submitted on November 30, 1968
Accepted on June 2, 1969


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