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Journal of Lipid Research, Vol. 10, 683-686, November 1969
Copyright © 1969 by Lipid Research, Inc.

Improved synthesis of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA)

A. I. Louw , I. Bekersky , and E. H. Mosbach

Department of Laboratory Diagnosis, Public Health Research Institute of the City of New York, Inc., and the Bureau of Laboratories, New York City Department of Health, New York 10016

An improved method for the chemical synthesis of HMG-CoA is described. The procedure is designed to prevent the formation of 3-acetoxy-HMG-CoA.

Supplementary key words 3-acetoxy-3-methylglutaric anhydride • 3-hydroxy-3-methylglutaric anhydride • 3-acetoxy-3-methylglutaryl CoA

Submitted on June 13, 1969
Accepted on August 6, 1969


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