Journal of Lipid Research, Vol. 11, 306-310, July 1970
Copyright © 1970 by Lipid Research, Inc.

Occurrence of ungulic acid in some epidermal tissues

E. Leikola , Elna Nieminen , and Anna-Maija Teppo

Department of Pharmacy, University of Helsinki, Helsinki, Finland

The lipids isolated from different animal tissues have been studied qualitatively, by TLC, for the occurrence of the ungulic acid fraction. This fraction was found in considerable amounts only in epidermal tissues and its keratinized derivatives. In the present study it was isolated from human keratinous epidermis, hair, and nails, pig bristles, wool, and feathers. The analytical results indicated that a lipid fraction from all of these sources contained ceramide, galactose, galactosamine, sulfate, and sialic acid in equimolar amounts, and that the fractions were similar to the ungulic acid isolated earlier from a horse's hoof.

Supplementary key words keratinous epidermis • hair • nail • wool • feather • pig bristles • ganglioside sulfate • fatty acids • thin-layer chromatography

Submitted on November 3, 1969
Accepted on March 17, 1970

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