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Journal of Lipid Research, Vol. 12, 71-75, January 1971
Copyright © 1971 by Lipid Research, Inc.

Study of the transfer of phospholipids from the endoplasmic reticulum to the outer and inner mitochondrial membranes

Marie-Thérèse Sauner and Marianne Lévy

Laboratoire de Physiologie de la Nutrition, Faculté des Sciences, 1 rue Victor Cousin, Paris 5°, France

Isolated mitochondria cannot synthesize their own phospholipids, there is only an exchange between exogenous and mitochondrial phospholipid fatty acids. In vitro, the endoplasmic reticulum phospholipids exchange with the phospholipids of the mitochondrial outer and inner membranes. Exchange of the endoplasmic reticulum phospholipids with those of the inner membrane is the same when the incubation is carried out with whole mitochondria or with mitochondria devoid of outer membranes.

Supplementary key words phosphatidylcholine • phosphatidylethanolamine • phosphatidylinositol • microsomes • acyltransferases

Submitted on June 24, 1970
Accepted on October 15, 1970


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