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Journal of Lipid Research, Vol. 13, 819-822, November 1972
Copyright © 1972 by Lipid Research, Inc.
Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232
Fatty acyl esters of N-hydroxysuccinimide have been used to directly N-acylate sphingenine or sphinganine, forming the corresponding ceramides. The reaction proceeds in excellent yield (84-96%) from small amounts of starting material (10-20 mg). The product ceramides are pure after one recrystallization.
Supplementary key words sphingenine sphinganine
Submitted on April 21, 1972
Accepted on July 10, 1972
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