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Journal of Lipid Research, Vol. 15, 432-435, July 1974
Copyright © 1974 by Lipid Research, Inc.

Tritiated glycerol triether as an oil phase marker in man

V. P. Gerskowitch and R. I. Russell

Department of Gastroenterology and University Department of Medicine, Royal Infirmary, Glasgow, G4 OSF, Scotland

³H-labeled glycerol triether has been suggested as a marker of the oil phase during digestion and absorption of a lipid test meal. This study examines the behavior of this isotope in the human alimentary tract. The results suggest that it is completely recovered from the gastrointestinal tract, and thus it remains solely with the oil phase of emulsions in vivo and with the oil phase of intestinal aspirates. ³H-labeled glycerol triether may thus be an appropriate marker of the oil phase for use in human studies of lipid absorption.

Supplementary key words triglyceride • absorption studies • inert marker

Submitted on November 2, 1973
Accepted on March 14, 1974

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