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Journal of Lipid Research, Vol 19, 985-991, Copyright © 1978 by Lipid Research, Inc.

ARTICLES

Studies of bile acid secretion by isolated rat hepatocytes

B Gardner and MS Chenouda

Bile acid secretion was studied in isolated rat hepatocytes cultured in medium supplemented with cofactors and succinate. Succinate as a respiratory substrate was found to be essential for bile acid synthesis. Feedback mechanism was demonstrated with different inhibitory potency of different bile acids on bile acid synthesis in isolated hepatocytes.
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This article has been cited by other articles:


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C Oshio and M. Phillips
Contractility of bile canaliculi: implications for liver function
Science, May 29, 1981; 212(4498): 1041 - 1042.
[Abstract] [PDF]


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