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Journal of Lipid Research, Vol. 2, 148-151, April 1961
Copyright © 1961 by Lipid Research, Inc.

The lipid residues in cytolipin H

Maurice M. Rapport , Vladimir P. Skipski , and Charles C. Sweeley

Department of Biochemistry, Albert Einstein College of Medicine, Yeshiva University, New York 61, N. Y.; and Division of Experimental Pathology, Sloan-Kettering Institute for Cancer Research, New York 21, N. Y.

Analyses were done of the individual fatty acids in two preparations of cytolipin H and the lipid bases in one preparation. A number of fatty acids were present, lignoceric acid predominating. No 2-hydroxy fatty acids were present. Of the lipid bases, 93% was sphingosine and 7% was a more unsaturated residue (dehydrosphingosine?). No dihydrosphingosine was present. Analyses of a number of cytolipin preparations showed them to be similar to cerebrosides derived from non-nervous animal tissues in having a nonuniform distribution of normal saturated fatty acids: C24, C22, and C16 acids were present in high concentration, and C20, C18, and C14 acids were present in very low concentration.

Submitted on September 29, 1960


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