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Journal of Lipid Research, Vol. 2, 268-270, July 1961
Copyright © 1961 by Lipid Research, Inc.
Department of Physical Chemistry, Isaac Albert Research Institute of the Jewish Chronic Disease Hospital, Brooklyn 3, New York
The fatty acid composition of human serum albumin (Cohn Fraction V) was determined by gas-liquid chromatography. Forty-three peaks were observed; 26 of these were identified by various methods. Eight of the identified peaks constituted about 90% of the total free fatty acids, and 65% of the total were unsaturated acids. The patterns of fatty acids bound to albumin were essentially the same as those found in plasma. However, quantitative differences were observed in the percentage of 18 carbon acids in the free fatty acids of human serum albumin samples as compared to plasma. Possible explanations to account for these differences are discussed.
Submitted on November 18, 1960
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