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Journal of Lipid Research, Vol. 2, 400-402, October 1961
Copyright © 1961 by Lipid Research, Inc.

Effect of ingested fat on fatty acid composition of serum lipoproteins

J. H. Bragdon and A. Karmen

Section on Metabolism and the Laboratory of Technical Development, National Heart Institute, National Institutes of Health, Bethesda 14, Maryland

The fatty acid composition of several serum lipoprotein fractions of a human subject was studied before and after the ingestion of a fat meal composed of corn oil. It was found that the fatty acids of the chylomicrons, low density lipoproteins (d < 1.019), and of the d > 1.21 fraction tend to resemble the fatty acids of the recently ingested fat. It was established that this resemblance was not the result of exchange in vitro from chylomicrons to other fractions. Similar changes in composition of the other lipoprotein fractions were also observed, but these were small in magnitude and not outside the range of experimental error.

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