J. Lipid Res. Acyl Labeled PIP's available August 1, 2008
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Journal of Lipid Research, Vol. 23, 197-200, January 1982
Copyright © 1982 by Lipid Research, Inc.

Synthesis of isotopically labeled saturated fatty acids

S. K. DasGupta , D. M. Rice , and R. G. Griffin

Francis Bitter National Magnet Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139

An approach to the synthesis of isotopically labeled saturated fatty acids is outlined which is based on the copper-catalyzed coupling of an ohgr-bromo acid with an isotopically labeled Grignard reagent. The method provides high yields of pure products and offers considerable flexibility in the type of isotopically enriched compound that can be prepared.—DasGupta, S. K., D. M. Rice, and R. G. Griffin. Synthesis of isotopically labeled saturated fatty acids.

Supplementary key words 2H and 13C • isotopic labels • saturated fatty acids

Submitted on May 11, 1981
Revised on August 18, 1981


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