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Journal of Lipid Research, Vol 23, 955-961, Copyright © 1982 by Lipid Research, Inc.

ARTICLES

Evidence for a compartmentation of brain microsomal diacylglycerol

L Binaglia, R Roberti, A Vecchini and G Porcellati

Phosphatidylcholine synthesis from CDP-[methyl-14C]choline and membrane- bound diacyl-[U-14C]-sn-glycerol, formed through the glycerol phosphate pathway, has been examined in vitro in rat brain microsomes. When labeled diacylglycerol was incubated in the presence of unlabeled CDP- choline, the rate of phospholipid labeling looked very different from that measured in incubations of unlabeled diacylglycerol with CDP- [methyl-14C]choline. Evidence is given that diacylglycerol formed through the glycerol phosphate pathway belongs to a metabolic pool separate from the bulk membrane diacylglycerol.
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J. Cao, L. Cheng, and Y. Shi
Catalytic properties of MGAT3, a putative triacylgycerol synthase
J. Lipid Res., March 1, 2007; 48(3): 583 - 591.
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