J. Lipid Res. Acyl Labeled PIP's available August 1, 2008
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Renshaw, P. F.
Right arrow Articles by Miller, K. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Renshaw, P. F.
Right arrow Articles by Miller, K. W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Journal of Lipid Research, Vol 24, 47-51, Copyright © 1983 by Lipid Research, Inc.

ARTICLES

On the nature of dilute aqueous cholesterol suspensions

PF Renshaw, AS Janoff and KW Miller

Cholesterol is commonly supposed to form a micelle in aqueous solution. We have reassessed this finding using a variety of techniques. Centrifugation sedimented cholesterol at all concentrations above 10(- 8) M. Density gradient analysis of more concentrated solutions revealed two bands whose densities corresponded to crystalline anhydrous cholesterol and crystalline cholesterol monohydrate. The monohydrate was characterized by light microscopy and phase transition. This band is also claimed to contain micelles, but no enhancement of perylene or diphenylhexatriene fluorescence could be detected. Some crystals of monohydrate could pass through 0.7-microns filters but not through 1.5- nm filters. Crystals of monohydrate were detected on the latter filters when solutions with cholesterol concentrations as low as 2.6 X 10(-8) M were filtered. Thus, under all conditions where micelles might be expected, we have detected micro-crystals of cholesterol monohydrate and we can find no independent evidence to support the existence of a cholesterol micelle.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 RNAHome page
U. F. Muller and D. P. Bartel
Improved polymerase ribozyme efficiency on hydrophobic assemblies
RNA, March 1, 2008; 14(3): 552 - 562.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. P. Heuck, C. G. Savva, A. Holzenburg, and A. E. Johnson
Conformational Changes That Effect Oligomerization and Initiate Pore Formation Are Triggered throughout Perfringolysin O upon Binding to Cholesterol
J. Biol. Chem., August 3, 2007; 282(31): 22629 - 22637.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. C. Shea, D. D. Head, K. D. R. Setchell, and D. W. Russell
Inaugural Article: Analysis of HSD3B7 knockout mice reveals that a 3{alpha}-hydroxyl stereochemistry is required for bile acid function
PNAS, July 10, 2007; 104(28): 11526 - 11533.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. L. McIntosh, A. M. Gallegos, B. P. Atshaves, S. M. Storey, D. Kannoju, and F. Schroeder
Fluorescence and Multiphoton Imaging Resolve Unique Structural Forms of Sterol in Membranes of Living Cells
J. Biol. Chem., February 14, 2003; 278(8): 6384 - 6403.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 All ASBMB Journals   Journal of Biological Chemistry 
 Molecular and Cellular Proteomics   ASBMB Today 
Copyright © 1983 by the American Society for Biochemistry and Molecular Biology.