J. Lipid Res. Neurobiology of Lipids (ISSN1683-5506)
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Journal of Lipid Research, Vol 24, 94-96, Copyright © 1983 by Lipid Research, Inc.

ARTICLES

Configuration at C-25 in 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta- cholestan-26-oic acid isolated from human bile

AK Batta, G Salen, S Shefer, B Dayal and GS Tint

This report describes the isolation of the natural isomer of 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid from human bile by a method that retains the configuration at C-25. The stereochemistry at C-25 in this bile acid was defined as 25R by a direct comparison with standard (25R)3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta- cholestan-26-oic acid.
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