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Journal of Lipid Research, Vol 29, 691-697, Copyright © 1988 by Lipid Research, Inc.
H Sugihara, N Yonemitsu, S Toda, S Miyabara, S Funatsumaru and T Matsumoto
Three-dimensional culture with collagen gel, developed recently for the in
vitro study of some mammalian cells in a more physiological condition than
a monolayer culture, was applied for a biological study of unilocular fat
cells. Successfully embedded in the gel, the unilocular fat cells were
shown to be able to keep their cellular function and actively proliferate.
These findings confirm that unilocular fat cells do undergo proliferation
under in vitro conditions as demonstrated in monolayer culture.
ARTICLES
Unilocular fat cells in three-dimensional collagen gel matrix culture
Department of Pathology, Saga Medical School, Japan.
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