HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mueller, P. S. Search for Related Content PubMed Articles by Mueller, P. S. Social Bookmarking                      What's this?

Journal of Lipid Research, Vol. 3, 92-94, January 1962
Copyright © 1962 by Lipid Research, Inc.

The absence of plasma free fatty acid response to epinephrine in vitamin-C-deprived guinea pigs

P. S. Mueller

Laboratory of Clinical Science, National Institute of Mental Health, Bethesda 14, Maryland

Plasma concentrations of free fatty acid (FFA) and blood glucose were measured in normal and 25-day scorbutic guinea pigs 15 minutes after injection of either saline or epinephrine. The normal group showed a large increase in FFA after epinephrine and a smaller increase after saline as compared to no injection at all. The scorbutic animals had no increase of FFA either after saline or epinephrine. The injection of 50 mg ascorbic acid intraperitoneally into 25-day scorbutic guinea pigs 5 hours before sacrifice restored to this group the normal response to epinephrine and saline. The mean plasma 17-OH corticosteroid concentration was 206.5 µg/100 ml for six 25-day scorbutic guinea pigs and was 71.5 µg/100 ml for six normal guinea pigs. Scorbutic animals had marked increases of glucose both after saline and epinephrine injections as compared to uninjected scorbutic animals.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?