| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Lipid Research, Vol 32, 859-866, Copyright © 1991 by Lipid Research, Inc.
ARTICLES |
KA Kieft, TM Bocan and BR Krause
Department of Pharmacology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, MI 48105.
A high-performance gel chromatography (HPGC) system has been developed which allows the unattended on-line determination of lipoprotein cholesterol distribution (VLDL-C, LDL-C, HDL-C), within 40 min, in microliter quantities of plasma using a single, relatively inexpensive column (Superose 6HR). The FAST cholesterol reagent (Sclavo) and a knitted PFTE Kratos reaction coil (Applied Biosystems) were found to provide optimal sensitivity, linearity, resolution, and dispersion characteristics. Validation is provided by comparison to target values for human quality control reference sera, and by comparing the values obtained by HPGC to the beta-quant method (LRC). The utility of the system is illustrated by comparing profiles from seven different species with normal or elevated plasma cholesterol concentrations. This technique allows rapid analysis of samples, regardless of species, without the use of precipitating agents or the ultracentrifuge. It could also be applied for the direct clinical determination of LDL- cholesterol.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  K. Miyauchi, N. Kayahara, M. Ishigami, H. Kuwata, H. Mori, H. Sugiuchi, T. Irie, A. Tanaka, S. Yamashita, and T. Yamamura Development of a Homogeneous Assay to Measure Remnant Lipoprotein Cholesterol Clin. Chem., December 1, 2007; 53(12): 2128 - 2135. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Chu, M. Miyazaki, W. C. Man, and J. M. Ntambi Stearoyl-Coenzyme A Desaturase 1 Deficiency Protects against Hypertriglyceridemia and Increases Plasma High-Density Lipoprotein Cholesterol Induced by Liver X Receptor Activation. Mol. Cell. Biol., September 1, 2006; 26(18): 6786 - 6798. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Porsgaard, X. Xu, and H. Mu The Form of Dietary Conjugated Linoleic Acid Does Not Influence Plasma and Liver Triacylglycerol Concentrations in Syrian Golden Hamsters J. Nutr., August 1, 2006; 136(8): 2201 - 2206. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. Leibowitz, R. J. Ardecky, M. F. Boehm, C. L. Broderick, M. A. Carfagna, D. L. Crombie, J. D'Arrigo, G. J. Etgen, M. M. Faul, T. A. Grese, et al. Biological Characterization of a Heterodimer-Selective Retinoid X Receptor Modulator: Potential Benefits for the Treatment of Type 2 Diabetes Endocrinology, February 1, 2006; 147(2): 1044 - 1053. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. P. Singh, R. Kauffman, W. Bensch, G. Wang, P. McClelland, J. Bean, C. Montrose, N. Mantlo, and A. Wagle Identification of a Novel Selective Peroxisome Proliferator-Activated Receptor {alpha} Agonist, 2-Methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic Acid (LY518674), That Produces Marked Changes in Serum Lipids and Apolipoprotein A-1 Expression Mol. Pharmacol., September 1, 2005; 68(3): 763 - 768. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Reifel-Miller, K. Otto, E. Hawkins, R. Barr, W. R. Bensch, C. Bull, S. Dana, K. Klausing, J.-A. Martin, R. Rafaeloff-Phail, et al. A Peroxisome Proliferator-Activated Receptor {alpha}/{gamma} Dual Agonist with a Unique in Vitro Profile and Potent Glucose and Lipid Effects in Rodent Models of Type 2 Diabetes and Dyslipidemia Mol. Endocrinol., June 1, 2005; 19(6): 1593 - 1605. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Wallace, M. Schwarz, P. Coward, J. Houze, J. K. Sawyer, K. L. Kelley, A. Chai, and L. L. Rudel Effects of peroxisome proliferator-activated receptor {alpha}/{delta} agonists on HDL-cholesterol in vervet monkeys J. Lipid Res., May 1, 2005; 46(5): 1009 - 1016. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Marchesi, E. A. Booth, T. Davis, C. L. Bisgaier, and B. R. Lucchesi Apolipoprotein A-IMilano and 1-Palmitoyl-2-oleoyl Phosphatidylcholine Complex (ETC-216) Protects the in Vivo Rabbit Heart from Regional Ischemia-Reperfusion Injury J. Pharmacol. Exp. Ther., December 1, 2004; 311(3): 1023 - 1031. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T.-S. Park, R. L. Panek, S. B. Mueller, J. C. Hanselman, W. S. Rosebury, A. W. Robertson, E. K. Kindt, R. Homan, S. K. Karathanasis, and M. D. Rekhter Inhibition of Sphingomyelin Synthesis Reduces Atherogenesis in Apolipoprotein E-Knockout Mice Circulation, November 30, 2004; 110(22): 3465 - 3471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. T. Cramer, B. Goetz, K. L. M. Hopson, G. J. Fici, R. M. Ackermann, S. C. Brown, C. L. Bisgaier, W. G. Rajeswaran, D. C. Oniciu, and M. E. Pape Effects of a novel dual lipid synthesis inhibitor and its potential utility in treating dyslipidemia and metabolic syndrome J. Lipid Res., July 1, 2004; 45(7): 1289 - 1301. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. K. Bowles, C. L. Heaps, J. R. Turk, K. K. Maddali, and E. M. Price Hypercholesterolemia inhibits L-type calcium current in coronary macro-, not microcirculation J Appl Physiol, June 1, 2004; 96(6): 2240 - 2248. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. P. Beyer, R. J. Schmidt, P. Foxworthy, Y. Zhang, J. Dai, W. R. Bensch, R. F. Kauffman, H. Gao, T. P. Ryan, X.-C. Jiang, et al. Coadministration of a Liver X Receptor Agonist and a Peroxisome Proliferator Activator Receptor-{alpha} Agonist in Mice: Effects of Nuclear Receptor Interplay on High-Density Lipoprotein and Triglyceride Metabolism in Vivo J. Pharmacol. Exp. Ther., June 1, 2004; 309(3): 861 - 868. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Chetiveaux, H. Nazih, V. Ferchaud-Roucher, G. Lambert, Y. Zair, M. Masson, K. Ouguerram, D. Bouhours, and M. Krempf The differential apoA-I enrichment of pre{beta}1 and {alpha}HDL is detectable by gel filtration separation J. Lipid Res., November 1, 2002; 43(11): 1986 - 1993. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Cao, T. P. Beyer, X. P. Yang, R. J. Schmidt, Y. Zhang, W. R. Bensch, R. F. Kauffman, H. Gao, T. P. Ryan, Y. Liang, et al. Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo J. Biol. Chem., October 11, 2002; 277(42): 39561 - 39565. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Chiesa, E. Monteggia, M. Marchesi, P. Lorenzon, M. Laucello, V. Lorusso, C. Di Mario, E. Karvouni, R. S. Newton, C. L. Bisgaier, et al. Recombinant Apolipoprotein A-IMilano Infusion Into Rabbit Carotid Artery Rapidly Removes Lipid From Fatty Streaks Circ. Res., May 17, 2002; 90(9): 974 - 980. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Usui, Y. Hara, S. Hosaki, and M. Okazaki A new on-line dual enzymatic method for simultaneous quantification of cholesterol and triglycerides in lipoproteins by HPLC J. Lipid Res., May 1, 2002; 43(5): 805 - 814. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. G. Cole, W. L. Nowatzke, C. L. Bisgaier, and B. R. Krause Method-dependent Changes in ""HDL-Cholesterol"" with Recombinant Apolipoprotein A-IMilano Infusion in Healthy Volunteers Clin. Chem., April 1, 2002; 48(4): 680 - 681. [Full Text] [PDF]
|
|
|
|
 |
|
 S. VanPatten, N. Ranginani, S. Shefer, L. B. Nguyen, L. Rossetti, and D. E. Cohen Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance Am J Physiol Gastrointest Liver Physiol, August 1, 2001; 281(2): G393 - G404. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. G. Robertson, M. A. Breider, and M. A. Milad Preclinical Safety Evaluation of Avasimibe in Beagle Dogs: An ACAT Inhibitor with Minimal Adrenal Effects Toxicol. Sci., February 1, 2001; 59(2): 324 - 334. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Fei, S. Maeda, H. Kirii, S. Fujigaki, N. Maekawa, H. Fujii, H. Wada, K. Saito, and M. Seishima Evaluation of Two Different Homogeneous Assays for LDL-Cholesterol in Lipoprotein-X-positive Serum Clin. Chem., September 1, 2000; 46(9): 1351 - 1356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. Garber, K. R. Kulkarni, and G. M. Anantharamaiah A sensitive and convenient method for lipoprotein profile analysis of individual mouse plasma samples J. Lipid Res., June 1, 2000; 41(6): 1020 - 1026. [Abstract] [Full Text]
|
|
|
|
|
|
J. R. Burnett, L. J. Wilcox, D. E. Telford, S. J. Kleinstiver, P. H. R. Barrett, R. S. Newton, and M. W. Huff The Magnitude of Decrease in Hepatic Very Low Density Lipoprotein Apolipoprotein B Secretion Is Determined by the Extent of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition in Miniature Pigs Endocrinology, November 1, 1999; 140(11): 5293 - 5302. [Abstract] [Full Text]
|
|
|
|
|
|
S. K. Cheema and L. B. Agellon Metabolism of Cholesterol Is Altered in the Liver of C3H Mice Fed Fats Enriched with Different C-18 Fatty Acids J. Nutr., September 1, 1999; 129(9): 1718 - 1724. [Abstract] [Full Text]
|
|
|
|
|
|
J. R. Burnett, L. J. Wilcox, D. E. Telford, S. J. Kleinstiver, P. H. R. Barrett, R. S. Newton, and M. W. Huff Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs J. Lipid Res., July 1, 1999; 40(7): 1317 - 1328. [Abstract] [Full Text]
|
|
|
|
|
|
R. G. Elkin, Z. Yan, Y. Zhong, S. S. Donkin, K. K. Buhman, J. A. Story, J. J. Turek, R. E. Porter Jr., M. Anderson, R. Homan, et al. Select 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors Vary in Their Ability to Reduce Egg Yolk Cholesterol Levels in Laying Hens through Alteration of Hepatic Cholesterol Biosynthesis and Plasma VLDL Composition J. Nutr., May 1, 1999; 129(5): 1010 - 1019. [Abstract] [Full Text]
|
|
|
|
|
|
C. J. Walkey, L. Yu, L. B. Agellon, and D. E. Vance Biochemical and Evolutionary Significance of Phospholipid Methylation J. Biol. Chem., October 16, 1998; 273(42): 27043 - 27046. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Innis-Whitehouse, X. Li, W. V. Brown, and N.-A. Le An efficient chromatographic system for lipoprotein fractionation using whole plasma J. Lipid Res., March 1, 1998; 39(3): 679 - 690. [Abstract] [Full Text]
|
|
|
|
|
|
C. L. Bisgaier, A. D. Essenburg, B. C. Barnett, B. J. Auerbach, S. Haubenwallner, T. Leff, A. D. White, P. Creger, M. E. Pape, T. J. Rea, et al. A novel compound that elevates high density lipoprotein and activates the peroxisome proliferator activated receptor J. Lipid Res., January 1, 1998; 39(1): 17 - 30. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. R. Burnett, L. J. Wilcox, D. E. Telford, S. J. Kleinstiver, P. H. R. Barrett, R. S. Newton, and M. W. Huff Inhibition of HMG-CoA Reductase by Atorvastatin Decreases Both VLDL and LDL Apolipoprotein B Production in Miniature Pigs Arterioscler. Thromb. Vasc. Biol., November 1, 1997; 17(11): 2589 - 2600. [Abstract] [Full Text]
|
|
|
|
|
|
W. V. Rodrigueza, K. D. Mazany, A. D. Essenburg, M. E. Pape, T. J. Rea, C. L. Bisgaier, and K. J. Williams Large Versus Small Unilamellar Vesicles Mediate Reverse Cholesterol Transport In Vivo Into Two Distinct Hepatic Metabolic Pools : Implications for the Treatment of Atherosclerosis Arterioscler. Thromb. Vasc. Biol., October 1, 1997; 17(10): 2132 - 2139. [Abstract] [Full Text]
|
|
|
|
|
|
P. G. Scheffer, S. J. L. Bakker, R. J. Heine, and T. Teerlink Measurement of low-density lipoprotein particle size by high-performance gel-filtration chromatography Clin. Chem., October 1, 1997; 43(10): 1904 - 1912. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Shaish, M. Pape, T. Rea, R. A. K. Srivastava, M. A. Latour, D. Hopkins, and G. Schonfeld Alcohol Increases Plasma Levels of Cholesterol Diet–Induced Atherogenic Lipoproteins and Aortic Atherosclerosis in Rabbits Arterioscler. Thromb. Vasc. Biol., June 1, 1997; 17(6): 1091 - 1097. [Abstract] [Full Text]
|
|
|
|
|
|
D. I. Draganov, P. L. Stetson, C. E. Watson, S. S. Billecke, and B. N. La Du Rabbit Serum Paraoxonase 3 (PON3) Is a High Density Lipoprotein-associated Lactonase and Protects Low Density Lipoprotein against Oxidation J. Biol. Chem., October 20, 2000; 275(43): 33435 - 33442. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| All ASBMB Journals | Journal of Biological Chemistry |
| Molecular and Cellular Proteomics | ASBMB Today |
