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Journal of Lipid Research, Vol 33, 441-443, Copyright © 1992 by Lipid Research, Inc.

ARTICLES

Bile acid and sterol solubilization in 2-hydroxypropyl-beta- cyclodextrin

J De Caprio, J Yun and NB Javitt
Division of Hepatic Diseases, New York University Medical Center 10016.

The use of 2-hydroxypropyl-beta-cyclodextrin has made it possible to prepare stable aqueous solutions of cholesterol, 26-hydroxycholesterol, 7 alpha-hydroxycholesterol, and monohydroxy bile acids such as lithocholic and 3 beta-hydroxy-5-cholenoic acids. These solutions are suitable for cell culture studies and for parenteral administration to animals.
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