J. Lipid Res.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sonnino, S.
Right arrow Articles by Tettamanti, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sonnino, S.
Right arrow Articles by Tettamanti, G.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Journal of Lipid Research, Vol 33, 1221-1226, Copyright © 1992 by Lipid Research, Inc.

ARTICLES

Preparation of lyso-GM1 (II3Neu5AcGgOse4-long chain bases) by a one-pot reaction

S Sonnino, D Acquotti, G Kirschner, A Uguaglianza, L Zecca, F Rubino and G Tettamanti
Department of Medical Chemistry and Biochemistry, Medical School, University of Milan, Italy.

A simple procedure is described for preparing lyso-GM1, a GM1 derivative that lacks the fatty acid moiety, starting from GM1 ganglioside using a one-pot reaction. Ganglioside deacylation was carried out in KOH/propan-1-ol in the absence of oxygen. The yield of lyso-GM1 under optimal conditions (6 h, 90 degrees C, 0.2 N KOH, 1 mM GM1) was 54%. The chemical structure of lyso-GM1 was determined by 1H- NMR and FAB-MS analyses, thus proving that the acetamide groups of galactosamine and sialic acid units were not affected during the deacylation reaction.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 GlycobiologyHome page
M. Kyogashima, K. Tamiya-Koizumi, T. Ehara, G. Li, R. Hu, A. Hara, T. Aoyama, and R. Kannagi
Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF MS
Glycobiology, August 1, 2006; 16(8): 719 - 728.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
S. Itonori, M. Takahashi, T. Kitamura, K. Aoki, J. T. Dulaney, and M. Sugita
Microwave-mediated analysis for sugar, fatty acid, and sphingoid compositions of glycosphingolipids
J. Lipid Res., March 1, 2004; 45(3): 574 - 581.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
O. Valiente, L. Mauri, R. Casellato, L. E. Fernandez, and S. Sonnino
Preparation of deacetyl-, lyso-, and deacetyl-lyso-GM3 by selective alkaline hydrolysis of GM3 ganglioside
J. Lipid Res., August 1, 2001; 42(8): 1318 - 1324.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Palestini, M. Pitto, G. Tedeschi, A. Ferraretto, M. Parenti, J. Brunner, and M. Masserini
Tubulin Anchoring to Glycolipid-enriched, Detergent-resistant Domains of the Neuronal Plasma Membrane
J. Biol. Chem., March 31, 2000; 275(14): 9978 - 9985.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 All ASBMB Journals   Journal of Biological Chemistry 
 Molecular and Cellular Proteomics   ASBMB Today 
Copyright © 1992 by the American Society for Biochemistry and Molecular Biology.