| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Lipid Research, Vol 36, 685-695, Copyright © 1995 by Lipid Research, Inc.
JA Bouwstra, GS Gooris, W Bras and DT Downing
The lipid and keratin structure of pig stratum corneum has been elucidated
by small- and wide-angle X-ray diffraction. The measurements were carried
out as a function of hydration and temperature. In addition, the stratum
corneum was measured after recrystallization of the lipids at various
temperatures. The results led us to conclude that the intercellular lipids
in the stratum corneum are organized in at least two different lamellar
structures with repeat distances of 6 and 13.2 nm. There is an indication
for the presence of a third phase with a periodicity of 9 nm. The
wide-angle pattern revealed a hexagonal (0.414 nm spacing) and liquid
lateral packing (approximately 0.46 nm spacing). The 0.414 nm reflection
started to decrease in intensity between 60 and 66 degrees C and
disappeared between 72 and 95 degrees C. Furthermore, crystalline
cholesterol has been indicated by both, wide- and small-angle X-ray
diffraction, while the reflections of alpha- keratin were observed in the
wide-angle X-ray diffraction pattern.
ARTICLES
Lipid organization in pig stratum corneum
Leiden/Amsterdam Center for Drug Research, Leiden, The Netherlands.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  G. S. Gooris and J. A. Bouwstra Infrared Spectroscopic Study of Stratum Corneum Model Membranes Prepared from Human Ceramides, Cholesterol, and Fatty Acids Biophys. J., April 15, 2007; 92(8): 2785 - 2795. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. G. Gibbs WATERPROOF COCKROACHES: THE EARLY WORK OF J. A. RAMSAY J. Exp. Biol., March 15, 2007; 210(6): 921 - 922. [Full Text] [PDF]
|
|
|
|
 |
|
 M. W. de Jager, G. S. Gooris, M. Ponec, and J. A. Bouwstra Lipid mixtures prepared with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behavior J. Lipid Res., December 1, 2005; 46(12): 2649 - 2656. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. W. de Jager, G. S. Gooris, I. P. Dolbnya, W. Bras, M. Ponec, and J. A. Bouwstra Novel lipid mixtures based on synthetic ceramides reproduce the unique stratum corneum lipid organization J. Lipid Res., May 1, 2004; 45(5): 923 - 932. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. J. McIntosh Organization of Skin Stratum Corneum Extracellular Lamellae: Diffraction Evidence for Asymmetric Distribution of Cholesterol Biophys. J., September 1, 2003; 85(3): 1675 - 1681. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Bouwstra, G. S. Gooris, F. E. R. Dubbelaar, and M. Ponec Phase behavior of lipid mixtures based on human ceramides: coexistence of crystalline and liquid phases J. Lipid Res., November 1, 2001; 42(11): 1759 - 1770. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Bouwstra, G. S. Gooris, F. E. R. Dubbelaar, and M. Ponec Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range J. Lipid Res., December 1, 1999; 40(12): 2303 - 2312. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. K. Pilgram , A. M. En, G. T. Oostergetel, H. K. Koerten, and J. A. Bouwstra Study on the lipid organization of stratum corneum lipid models by (cryo-) electron diffraction J. Lipid Res., August 1, 1998; 39(8): 1669 - 1676. [Abstract] [Full Text]
|
|
|
|
|
|
J. A. Bouwstra, G. S. Gooris, F. E. R. Dubbelaar, A. M. Weerheim, A. P. IJzerman, and M. Ponec Role of ceramide 1 in the molecular organization of the stratum corneum lipids J. Lipid Res., January 1, 1998; 39(1): 186 - 196. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| All ASBMB Journals | Journal of Biological Chemistry |
| Molecular and Cellular Proteomics | ASBMB Today |
