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Journal of Lipid Research, Vol. 5, 57-62, January 1964
Copyright © 1964 by Lipid Research, Inc.

Serum lipids in choline-deficient male and female rats

J. Tinoco , Angela Shannon , and Richard L. Lyman

Department of Nutritional Sciences, University of California, Berkeley, California

Serum lipids from normal and choline-deficient male and female rats were fractionated on silicic acid. Total cholesterol, phosphorus, and fatty acid compositions were determined on serum cholesterol esters, triglycerides, phospholipids, and a small mixed fraction. Choline deficiency reduced the concentration of all classes of lipids in both sexes. Decreases in the phospholipid fractions of both sexes, and in cholesterol ester fractions of female rats, were largely due to preferential decreases in their arachidonic acid components, but the fatty acids in triglycerides decreased uniformly in both sexes.

Submitted on March 28, 1963
Accepted on September 5, 1963


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