J. Lipid Res.  Neurobiology of Lipids (ISSN1683-5506)
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Journal of Lipid Research, Vol. 6, 552-555, October 1965
Copyright © 1965 by Lipid Research, Inc.

Phospholipid composition of chick brain during development

T. J. Siek and R. W. Newburgh

Science Research Institute and Department of Chemistry, Oregon State University, Corvallis, Oregon

The phospholipid composition of chick embryo brain was examined over the interval 4-18 days of incubation. Phosphatidyl ethanolamine accounted for about 25% of the total lipid phosphorus during this interval, while phosphatidyl choline decreased from 70 to 50%. Sphingomyelin formed a relatively low fraction of the total phospholipid. The sum of inositol phosphatides and phosphatidyl serine was about 5%, with slight variation during the interval studied. A phospholipid resembling cardiolipin was detected. Its content increased to 4% during this incubation period.

Supplementary key words brain • phospholipids • chick embryo • phosphatidyl choline • phosphatidyl ethanolamine • phosphatidyl serine • sphingomyelin • phosphatidyl inositol • cardiolipin

Submitted on February 15, 1965
Accepted on June 23, 1965


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