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Journal of Lipid Research, Vol. 7, 174-175, January 1966
Copyright © 1966 by Lipid Research, Inc.

Synthesis of fatty acid anhydrides by reaction with dicyclohexylcarbodiimide

Z. Selinger and Y. Lapidot

Department of Biological Chemistry, The Hebrew University, Jerusalem, Israel

A simple method is described for the preparation of caprylic, palmitic, stearic, and oleic anhydrides. Reaction of the free fatty acid and dicyclohexylcarbodiimide in carbon tetrachloride at room temperature gives the corresponding anhydrides in high yield (87-94%).

Supplementary key words caprylic • palmitic • stearic • oleic • fatty acid • anhydride • preparation • dicyclohexylcarbodiimide

Submitted on August 16, 1965
Accepted on September 16, 1965

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