Submitted on October 11, 2006
Accepted on October 25, 2006
Proteomics approaches to the systems biology of cardiovascular diseases
Thomas A. Drake and Peipei Ping
Pathology and Laboratory Medicine, UCLA, Los Angeles, CA 90095-1732
Corresponding Author: tdrake{at}mednet.ucla.edu
Proteins play a central role in a systems view of biologic processes. This review provides an overview of proteomics from a systems perspective. We survey the key tools and methodologies employed, present examples of how these are currently being used in the systems biology context, and discuss future directions.