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J. Lipid Res.
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A more recent version of this article appeared on April 1, 2009

Papers In Press, published online ahead of print November 17, 2008
J. Lipid Res., doi:10.1194/jlr.R800057-JLR200
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Submitted on October 23, 2008
Revised on November 10, 2008
Accepted on November 16, 2008

Adipocyte metabolism and obesity

Alan D. Attie and Philipp E. Scherer

Biochemistry, University of Wisconsin-Madison, Madison, WI 53706

Corresponding Author: adattie{at}wisc.edu

Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling.


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Related Webpages:

JLR 50th Anniversary Collections
Anniversary Collection:: Lipids in Health and Disease



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