|
 |
|
|||||||
|
|||||||||
Papers In Press, published online ahead of print December 20, 2008
J. Lipid Res., doi:10.1194/jlr.R800098-JLR200
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Plant Physiology, Swammerdam Insititute for Life Sciences, University of Amsterdam, Amsterdam NL-1098SM
Corresponding Author: t.munnik{at}uva.nl
Since the discovery of the phosphoinositide/phospholipase C (PI/PLC) system in animal systems, we know that phospholipids are much more then just structural components of biological membranes. In the beginning, this idea was fairly straightforward. Receptor stimulation activates PLC which hydrolyses phosphatidylinositol4,5-bisphosphate [PtdIns(4,5)P2] into two second messengers: Inositol 1,4,5-trisphosphate (InsP3) and diacylglycerol (DAG). While InsP3 difuses into the cytosol and triggers the release of calcium from an internal store via ligand-gated calcium channels, DAG remains in the membrane where it recruits and activates members of the PKC family. The increase in calcium, together with the change in phosphorylation status, (in)activates a variety of protein targets, leading to a massive reprogramming, allowing the cell to appropriately respond to the extracellular stimulus. Later, it became obvious that not just PLC, but a variety of other phospholipid-metabolizing enzymes were activated, including phospholipase A (PLA), phospholipase D (PLD) and PI 3-kinase (PI3K). More recently, it has become apparent that PtdIns4P and PtdIns(4,5)P2 are not just signal precursors, but can also function as signaling molecules themselves. While plants contain most of the components described above (1-5), and evidence for their role in cell signaling is progressively increasing, major differences between plants and the mamalian paradigms exist. Below, these are described, 'in a nutshell'.
Revised on December 16, 2008
Accepted on December 17, 2008
Plant phospholipid signaling - 'in a nutshell'
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Related Webpages:
This article has been cited by other articles:
|
|
 |
|
  E. Madrid and P. Corchete Silymarin secretion and its elicitation by methyl jasmonate in cell cultures of Silybum marianum is mediated by phospholipase D-phosphatidic acid J. Exp. Bot., March 1, 2010; 61(3): 747 - 754. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Monreal, F. McLoughlin, C. Echevarria, S. Garcia-Maurino, and C. Testerink Phosphoenolpyruvate Carboxylase from C4 Leaves Is Selectively Targeted for Inhibition by Anionic Phospholipids Plant Physiology, February 1, 2010; 152(2): 634 - 638. [Full Text] [PDF]
|
|
|
|
 |
|
 A. Kirik and M. B. Mudgett SOBER1 phospholipase activity suppresses phosphatidic acid accumulation and plant immunity in response to bacterial effector AvrBsT PNAS, December 1, 2009; 106(48): 20532 - 20537. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Zhang, H. Zhu, Q. Zhang, M. Li, M. Yan, R. Wang, L. Wang, R. Welti, W. Zhang, and X. Wang Phospholipase D{alpha}1 and Phosphatidic Acid Regulate NADPH Oxidase Activity and Production of Reactive Oxygen Species in ABA-Mediated Stomatal Closure in Arabidopsis PLANT CELL, August 1, 2009; 21(8): 2357 - 2377. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Darwish, C. Testerink, M. Khalil, O. El-Shihy, and T. Munnik Phospholipid Signaling Responses in Salt-Stressed Rice Leaves Plant Cell Physiol., May 1, 2009; 50(5): 986 - 997. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| All ASBMB Journals | Journal of Biological Chemistry |
| Molecular and Cellular Proteomics | ASBMB Today |