J. Lipid Res.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

A more recent version of this article appeared on February 1, 2004

Papers In Press, published online ahead of print November 1, 2003
J. Lipid Res., doi:10.1194/jlr.M300331-JLR200
This Article
Right arrow Full Text (Accepted Manuscript)
Right arrow All Versions of this Article:
M300331-JLR200v1
45/2/281    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Colsch, B.
Right arrow Articles by Baumann, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Colsch, B.
Right arrow Articles by Baumann, N.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Submitted on July 25, 2003
Revised on October 29, 2003
Accepted on November 1, 2003

Characterization of the ceramide moieties of sphingoglycolipids from mouse brain by electrospray-tandem mass spectrometry: Identification of ceramides containing sphingadienine

Benoit Colsch, Carlos Afonso, Iuliana Popa, Jacques Portoukalian, Francoise Fournier, Jean-Claude Tabet, and Nicole Baumann

Department of Neurochemistry, INSERM Unit 495, 75651, Paris Cedex 13

Corresponding Author: baumann{at}ccr.jussieu.fr

Sphingoglycolipids (SGL) are cell membrane constituents. As the ceramide structure influences the biological properties of the SGL, we characterized by electrospray tandem mass spectrometry the molecular species of ceramides present in SGL of mouse brain. We report here for the first time the presence in mammalian brain of sphingadienine (d18:2). Sphingenine (d18:1) is present in all SGL species in contrast to eicosasphingenine (d20:1) which is only a constituent of gangliosides. Sphingadienine is present in galactocerebrosides and sulfatides. Free ceramides contain the three types of bases. Thus there could be two separate pools of free ceramides (d18:1; d18:2) and (d20:1; d18:1) as precursors of complex SGL.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J. Lipid Res.Home page
K. Ikeda, T. Shimizu, and R. Taguchi
Targeted analysis of ganglioside and sulfatide molecular species by LC/ESI-MS/MS with theoretically expanded multiple reaction monitoring
J. Lipid Res., December 1, 2008; 49(12): 2678 - 2689.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
H. Fyrst, X. Zhang, D. R. Herr, H. S. Byun, R. Bittman, V. H. Phan, G. L. Harris, and J. D. Saba
Identification and characterization by electrospray mass spectrometry of endogenous Drosophila sphingadienes
J. Lipid Res., March 1, 2008; 49(3): 597 - 606.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
M. Valsecchi, L. Mauri, R. Casellato, S. Prioni, N. Loberto, A. Prinetti, V. Chigorno, and S. Sonnino
Ceramide and sphingomyelin species of fibroblasts and neurons in culture
J. Lipid Res., February 1, 2007; 48(2): 417 - 424.
[Abstract] [Full Text] [PDF]

Home page
 GlycobiologyHome page
M. Kyogashima, K. Tamiya-Koizumi, T. Ehara, G. Li, R. Hu, A. Hara, T. Aoyama, and R. Kannagi
Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF MS
Glycobiology, August 1, 2006; 16(8): 719 - 728.
[Abstract] [Full Text] [PDF]

Home page
 J BiochemHome page
Y. Suzuki, M. Suzuki, E. Ito, N. Goto-Inoue, K. Miseki, J. Iida, Y. Yamazaki, M. Yamada, and A. Suzuki
Convenient Structural Analysis of Glycosphingolipids Using MALDI-QIT-TOF Mass Spectrometry with Increased Laser Power and Cooling Gas Flow.
J. Biochem., April 1, 2006; 139(4): 771 - 777.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
 All ASBMB Journals   Journal of Biological Chemistry 
 Molecular and Cellular Proteomics   ASBMB Today 
Copyright © 2003 by the American Society for Biochemistry and Molecular Biology.