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COVER: Proposed compartmentalization of bile acid conjugation with taurine and glycine in the human liver cell. In cells located in the periportal regions the left side pathway may dominate, and in cells located in the pericentral regions the right side pathway may dominate. 1, Peroxisomal bile acid-CoA:amino acid N-acyltransferase; 2, peroxisomal bile acid-CoA thioesterase; 3, cytosolic bile acid-CoA:amino acid N--acyltransferase; 4, cytosolic bile acid-CoA thioesterase; 5, microsomal bile acid-CoA synthetase. (See Solaas et al., p. 1154.)
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Copyright © 2003 by Lipid Research, Inc.