J. Lipid Res.
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About the Cover

Cover Figure


COVER: Fluorescence photomicrographs of the three-dimensional distribution of apolipoprotein B (apoB) in control (top row) and brefeldin-A-treated (bottom row) HepG2 cells following a 2 h pulse with puromycin to deplete apoB. In control cells, apoB is seen throughout the endoplasmic reticulum (ER) as a low-intensity purple-blue signal. The brighter yellow-orange signal shows apoB in Golgi. In brefeldin-A-treated cells, transport of apoB from ER to Golgi is prevented and apoB accumulates in the central ER region of the cell. (See Sakata, Philips, and Dixon, p. 1947.)
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