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COVER: Freeze-etch electron micrograph of a macrophage foam cell located in the intima of a cardiac valve from a rabbit maintained on a high fat diet for 2 weeks. The cytoplasm of the macrophage is filled with large lipid droplets typical of cholesteryl esters and with clusters of various sized lipid particles within membrane-bound compartments. (See Haberland et al. p. 605.)
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