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COVER: Three-dimensional confocal images of a cholesterol-loaded aortic endothelial cell stained with HDL (red fluorescence), caveolin-1 (green fluorescence), and 2-actin (blue fluorescence) (A-C). In a lateral view of the image (B, C), 2-actin was present in the cytoplasm and caveolin-1 was on the cell surface. HDL was revealed only on the cell surface or invaginations into the cell. A cartoon diagram shows that HDL was located on the membrane invaginations (arrows) (D). (See Chao et al., p.1094.)
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