About the Cover
COVER:
Coimmunolocalization of lysosomes and 
6 apoA-I
cytoplasmic inclusions is shown in a single transfected COS-1 cell
where N labels the nucleus. The anti-apoA-I antibodies cover the surface of the
6 apoA-I-containing lipid-protein structures, yielding a
fluorescence pattern similar to a "bagel" (green). The overlay of an image for the organelle-specific lysosomal marker, cathepsin-D, is labeled with rhodamine (pink), which, for the
6 apoA-I structures, indicates that the majority of the "bagels"
are not coincident with lysosomes (yellow).
Classical neutral lipid droplets were also visualized using osmium-thiocarbohydrazide-osmium
and are colored blue.
(See Bhat et al., p.
1207.)
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Copyright © 2004 by the American Society for Biochemistry and Molecular Biology.
