HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

COVER: Phosphatidylinositol transfer protein α (PITPα; background ribbon diagram) binds phosphatidylinositol (PtdIns) or phosphatidylcholine (PtdCho). Transgenic mice expressing only a mutant Pitpα^T59D specifically defective in PtdIns binding (bottom panels; T₅₉ side chain at left, T₅₉D side chain at right) recapitulate the fatal course of neurodegenerative and intestinal/hepatic steatotic disease that characterizes Pitpα nullizygous mice. (See Alb et al., p. 1857.)
[Table of Contents]