Editorials:

Edward A. Dennis and Joseph L. Witztum

New Commentary section to highlight significant JLR articles
J. Lipid Res. 2008 49: 1. [Full Text] [PDF]  

Commentary:

Roger A. Davis

Resolving the mechanism of bile acid negative-feedback regulation, a Journal of Lipid Research tradition
J. Lipid Res. 2008 49: 2-3. [Full Text] [PDF]  

Thematic Reviews:

David R. Drake, Kim A. Brogden, Deborah V. Dawson, and Philip W. Wertz

Thematic Review Series: Skin Lipids. Antimicrobial lipids at the skin surface
J. Lipid Res. 2008 49: 4-11. First Published on September 28, 2007; doi:10.1194/jlr.R700016-JLR200 [Abstract] [Full Text] [PDF]  

Research Articles:

Carmen E. Perrone, Dwight A. L. Mattocks, George Hristopoulos, Jason D. Plummer, Rozlyn A. Krajcik, and Norman Orentreich

Methionine restriction effects on 11β-HSD1 activity and lipogenic/lipolytic balance in F344 rat adipose tissue
J. Lipid Res. 2008 49: 12-23. First Published on October 1, 2007; doi:10.1194/jlr.M700194-JLR200 [Abstract] [Full Text] [PDF]  

David T. Valenta, Joshua J. Bulgrien, David J. Bonnet, and Linda K. Curtiss

Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency
J. Lipid Res. 2008 49: 24-32. First Published on October 10, 2007; doi:10.1194/jlr.M700228-JLR200 [Abstract] [Full Text] [PDF]  

Daming Tang, Jonathan Lu, Jeffrey P. Walterscheid, Hsin-Hung Chen, David A. Engler, Tatsuya Sawamura, Po-Yuan Chang, Hazim J. Safi, Chao-Yuh Yang, and Chu-Huang Chen

Electronegative LDL circulating in smokers impairs endothelial progenitor cell differentiation by inhibiting Akt phosphorylation via LOX-1
J. Lipid Res. 2008 49: 33-47. First Published on October 1, 2007; doi:10.1194/jlr.M700305-JLR200 [Abstract] [Full Text] [PDF]  

Giuseppe Astarita, Faizy Ahmed, and Daniele Piomelli

Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain
J. Lipid Res. 2008 49: 48-57. First Published on October 23, 2007; doi:10.1194/jlr.M700354-JLR200 [Abstract] [Full Text] [PDF]  

Dmitry Namgaladze, Andreas Kollas, and Bernhard Brüne

Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling
J. Lipid Res. 2008 49: 58-65. First Published on September 21, 2007; doi:10.1194/jlr.M700100-JLR200 [Abstract] [Full Text] [PDF]  

Chan-Jung Liang, Harlan E. Ives, Chuen-Mao Yang, and Yunn-Hwa Ma

20-HETE inhibits the proliferation of vascular smooth muscle cells via transforming growth factor-β
J. Lipid Res. 2008 49: 66-73. First Published on October 4, 2007; doi:10.1194/jlr.M700155-JLR200 [Abstract] [Full Text] [PDF]  

Abdelmadjid K. Hihi, Marie-Claude Beauchamp, Robyn Branicky, Annick Desjardins, Isabel Casanova, Marie-Pierre Guimond, Melissa Carroll, Melanie Ethier, Irenej Kianicka, Kevin McBride, and Siegfried Hekimi

Evolutionary conservation of drug action on lipoprotein metabolism-related targets
J. Lipid Res. 2008 49: 74-83. First Published on September 27, 2007; doi:10.1194/jlr.M700167-JLR200 [Abstract] [Full Text] [PDF]  

Myoung Sook Han, Sun Young Park, Koei Shinzawa, Sunshin Kim, Kun Wook Chung, Ji-Hyun Lee, Choon Hyuck Kwon, Kwang-Woong Lee, Joon-Hyoek Lee, Cheol Keun Park, Woo Jin Chung, Jae Seok Hwang, Ji-Jing Yan, Dong-Keun Song, Yoshihide Tsujimoto, and Myung-Shik Lee

Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes
J. Lipid Res. 2008 49: 84-97. First Published on October 18, 2007; doi:10.1194/jlr.M700184-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data  

Angela A. Wendel, Aparna Purushotham, Li-Fen Liu, and Martha A. Belury

Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice
J. Lipid Res. 2008 49: 98-106. First Published on September 28, 2007; doi:10.1194/jlr.M700195-JLR200 [Abstract] [Full Text] [PDF]  

Laurent Yvan-Charvet, Tamara A. Pagler, Nan Wang, Takafumi Senokuchi, May Brundert, Hongna Li, Franz Rinninger, and Alan R. Tall

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL
J. Lipid Res. 2008 49: 107-114. First Published on October 24, 2007; doi:10.1194/jlr.M700200-JLR200 [Abstract] [Full Text] [PDF]  

Nongnuch Settasatian, Philip J. Barter, and Kerry-Anne Rye

Remodeling of apolipoprotein E-containing spherical reconstituted high density lipoproteins by phospholipid transfer protein
J. Lipid Res. 2008 49: 115-126. First Published on October 5, 2007; doi:10.1194/jlr.M700220-JLR200 [Abstract] [Full Text] [PDF]  

Richard E. Morton, Hannah M. Gnizak, Diane J. Greene, Kyung-Hyun Cho, and Victor M. Paromov

Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects
J. Lipid Res. 2008 49: 127-135. First Published on September 27, 2007; doi:10.1194/jlr.M700258-JLR200 [Abstract] [Full Text] [PDF]  

Miranda Van Eck, Menno Hoekstra, Ruud Out, I. Sophie T. Bos, J. Kar Kruijt, Reeni B. Hildebrand, and Theo J. C. Van Berkel

Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo
J. Lipid Res. 2008 49: 136-146. First Published on October 22, 2007; doi:10.1194/jlr.M700355-JLR200 [Abstract] [Full Text] [PDF]  

Chuck T. Chen, David W. L. Ma, John H. Kim, Howard T. J. Mount, and Richard P. Bazinet

The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations
J. Lipid Res. 2008 49: 147-152. First Published on October 11, 2007; doi:10.1194/jlr.M700386-JLR200 [Abstract] [Full Text] [PDF]  

Eduardo N. Maldonado, Nathan L. Alderson, Paula V. Monje, Patrick M. Wood, and Hiroko Hama

FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelin
J. Lipid Res. 2008 49: 153-161. First Published on September 27, 2007; doi:10.1194/jlr.M700400-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ho-Joo Lee, Jagadeesh S. Rao, Lisa Chang, Stanley I. Rapoport, and Richard P. Bazinet

Chronic N-methyl-D-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat
J. Lipid Res. 2008 49: 162-168. First Published on October 23, 2007; doi:10.1194/jlr.M700406-JLR200 [Abstract] [Full Text] [PDF]  

Paul T. Tarr and Peter A. Edwards

ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2
J. Lipid Res. 2008 49: 169-182. First Published on October 4, 2007; doi:10.1194/jlr.M700364-JLR200 [Abstract] [Full Text] [PDF]  

Kosuke Hashimoto, Akiyasu C. Yoshizawa, Shujiro Okuda, Keiichi Kuma, Susumu Goto, and Minoru Kanehisa

The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes
J. Lipid Res. 2008 49: 183-191. First Published on October 7, 2007; doi:10.1194/jlr.M700377-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data  

Georgette M. Buga, Joy S. Frank, Giuliano A. Mottino, Ashkan Hakhamian, Ajay Narasimha, Andrew D. Watson, Babak Yekta, Mohamad Navab, Srinivasa T. Reddy, G. M. Anantharamaiah, and Alan M. Fogelman

D-4F reduces EO6 immunoreactivity, SREBP-1c mRNA levels, and renal inflammation in LDL receptor-null mice fed a Western diet
J. Lipid Res. 2008 49: 192-205. First Published on October 9, 2007; doi:10.1194/jlr.M700433-JLR200 [Abstract] [Full Text] [PDF]  

Tanya D. Russell, Carol A. Palmer, David J. Orlicky, Elise S. Bales, Benny Hung-Junn Chang, Lawrence Chan, and James L. McManaman

Mammary glands of adipophilin-null mice produce an amino-terminally truncated form of adipophilin that mediates milk lipid droplet formation and secretion
J. Lipid Res. 2008 49: 206-216. First Published on October 5, 2007; doi:10.1194/jlr.M700396-JLR200 [Abstract] [Full Text] [PDF]  

Marcia L. E. MacDonald, Roshni R. Singaraja, Nagat Bissada, Piers Ruddle, Russell Watts, Joanna M. Karasinska, William T. Gibson, Catherine Fievet, Jean E. Vance, Bart Staels, and Michael R. Hayden

Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice
J. Lipid Res. 2008 49: 217-229. First Published on October 24, 2007; doi:10.1194/jlr.M700478-JLR200 [Abstract] [Full Text] [PDF]  

Methods:

Hong Li, Paul N. Black, Aalap Chokshi, Angel Sandoval-Alvarez, Ravi Vatsyayan, Whitney Sealls, and Concetta C. DiRusso

High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias
J. Lipid Res. 2008 49: 230-244. First Published on October 10, 2007; doi:10.1194/jlr.D700015-JLR200 [Abstract] [Full Text] [PDF]  

Philip W. Connelly, Graham F. Maguire, Clive M. Picardo, John F. Teiber, and Dragomir Draganov

Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma
J. Lipid Res. 2008 49: 245-250. First Published on September 28, 2007; doi:10.1194/jlr.D700022-JLR200 [Abstract] [Full Text] [PDF]  

Per Haberkant, Oliver Schmitt, F.-Xabier Contreras, Christoph Thiele, Kentaro Hanada, Hein Sprong, Constanze Reinhard, Felix T. Wieland, and Britta Brügger

Protein-sphingolipid interactions within cellular membranes
J. Lipid Res. 2008 49: 251-262. First Published on September 28, 2007; doi:10.1194/jlr.D700023-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data  

Calendar:

Calendar
J. Lipid Res. 2008 49: 263-264. [Full Text] [PDF]  

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