Commentary:

Carl Grunfeld and Kenneth R. Feingold

HDL and innate immunity: a tale of two apolipoproteins
J. Lipid Res. 2008 49: 1605-1606. First Published on May 31, 2008; doi:10.1194/jlr.E800011-JLR200 [Full Text] [PDF]    

Thematic Reviews:

Michael Schlame

Thematic Review Series: Glycerolipids. Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes
J. Lipid Res. 2008 49: 1607-1620. First Published on December 12, 2007; doi:10.1194/jlr.R700018-JLR200 [Abstract] [Full Text] [PDF]    

Research Articles:

Yunlong Wang, Xuewei Zhu, Gang Wu, Le Shen, and Baosheng Chen

Effect of lipid-bound apoA-I cysteine mutants on lipopolysaccharide-induced endotoxemia in mice
J. Lipid Res. 2008 49: 1640-1645. First Published on May 5, 2008; doi:10.1194/jlr.M700446-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Hong Du, Terri L. Cameron, Stephen J. Garger, Gregory P. Pogue, Lee A. Hamm, Earl White, Kathleen M. Hanley, and Gregory A. Grabowski

Wolman disease/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice
J. Lipid Res. 2008 49: 1646-1657. First Published on April 15, 2008; doi:10.1194/jlr.M700482-JLR200 [Abstract] [Full Text] [PDF]    

Stephen J. Peterson, George Drummond, Dong Hyun Kim, Ming Li, Adam L. Kruger, Susumu Ikehara, and Nader G. Abraham

L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice
J. Lipid Res. 2008 49: 1658-1669. First Published on April 19, 2008; doi:10.1194/jlr.M800046-JLR200 [Abstract] [Full Text] [PDF]    

Xiao Shu, Robert O. Ryan, and Trudy M. Forte

Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment
J. Lipid Res. 2008 49: 1670-1676. First Published on April 30, 2008; doi:10.1194/jlr.M800111-JLR200 [Abstract] [Full Text] [PDF]    

Elias N. Glaros, Woojin S. Kim, Kerry-Anne Rye, James A. Shayman, and Brett Garner

Reduction of plasma glycosphingolipid levels has no impact on atherosclerosis in apolipoprotein E-null mice
J. Lipid Res. 2008 49: 1677-1681. First Published on May 8, 2008; doi:10.1194/jlr.E800005-JLR200 [Abstract] [Full Text] [PDF]    

David Masson, Mohamed Qatanani, Anne Laure Sberna, Rui Xiao, Jean Paul Pais de Barros, Jacques Grober, Valerie Deckert, Anne Athias, Philippe Gambert, Laurent Lagrost, David D. Moore, and Mahfoud Assem

Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice
J. Lipid Res. 2008 49: 1682-1691. First Published on April 27, 2008; doi:10.1194/jlr.M700374-JLR200 [Abstract] [Full Text] [PDF]    

Charlotte Andersson, M. Rabie Al-Turkmani, Juanito E. Savaille, Ragheed Alturkmani, Waddah Katrangi, Joanne E. Cluette-Brown, Munir M. Zaman, Michael Laposata, and Steven D. Freedman

Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism
J. Lipid Res. 2008 49: 1692-1700. First Published on April 25, 2008; doi:10.1194/jlr.M700388-JLR200 [Abstract] [Full Text] [PDF]    

Kathy L. E. Klos, Eric Boerwinkle, Robert E. Ferrell, Stephen T. Turner, and Alanna C. Morrison

ESR1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study
J. Lipid Res. 2008 49: 1701-1706. First Published on April 30, 2008; doi:10.1194/jlr.M700490-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Mercedes Camacho, Cristina Rodríguez, Juliana Salazar, José Martínez-González, Josep Ribalta, José-Román Escudero, Lluís Masana, and Luis Vila

Retinoic acid induces PGI synthase expression in human endothelial cells
J. Lipid Res. 2008 49: 1707-1714. First Published on May 5, 2008; doi:10.1194/jlr.M700559-JLR200 [Abstract] [Full Text] [PDF]    

Alexandrine During, Sundari Doraiswamy, and Earl H. Harrison

Xanthophylls are preferentially taken up compared with β-carotene by retinal cells via a SRBI-dependent mechanism
J. Lipid Res. 2008 49: 1715-1724. First Published on April 19, 2008; doi:10.1194/jlr.M700580-JLR200 [Abstract] [Full Text] [PDF]    

Leanne K. Hein, Stephen Duplock, John J. Hopwood, and Maria Fuller

Lipid composition of microdomains is altered in a cell model of Gaucher disease
J. Lipid Res. 2008 49: 1725-1734. First Published on April 21, 2008; doi:10.1194/jlr.M800092-JLR200 [Abstract] [Full Text] [PDF]    

Miki Igarashi, Kaizong Ma, Lisa Chang, Jane M. Bell, and Stanley I. Rapoport

Rat heart cannot synthesize docosahexaenoic acid from circulating -linolenic acid because it lacks elongase-2
J. Lipid Res. 2008 49: 1735-1745. First Published on May 1, 2008; doi:10.1194/jlr.M800093-JLR200 [Abstract] [Full Text] [PDF]    

Anna Cabré, Iolanda Lázaro, Josefa Girona, Josep Maria Manzanares, Francesc Marimón, Núria Plana, Mercedes Heras, and Lluís Masana

Plasma fatty acid binding protein 4 is associated with atherogenic dyslipidemia in diabetes
J. Lipid Res. 2008 49: 1746-1751. First Published on April 17, 2008; doi:10.1194/jlr.M800102-JLR200 [Abstract] [Full Text] [PDF]    

Madhumita Guha, Donald L. Gantz, and Olga Gursky

Effects of acyl chain length, unsaturation, and pH on thermal stability of model discoidal HDLs
J. Lipid Res. 2008 49: 1752-1761. First Published on May 1, 2008; doi:10.1194/jlr.M800106-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Judith Storch, Yin Xiu Zhou, and William S. Lagakos

Metabolism of apical versus basolateral sn-2-monoacylglycerol and fatty acids in rodent small intestine
J. Lipid Res. 2008 49: 1762-1769. First Published on April 17, 2008; doi:10.1194/jlr.M800116-JLR200 [Abstract] [Full Text] [PDF]    

Akash Das, Matthew A. Davis, and Lawrence L. Rudel

Identification of putative active site residues of ACAT enzymes
J. Lipid Res. 2008 49: 1770-1781. First Published on May 13, 2008; doi:10.1194/jlr.M800131-JLR200 [Abstract] [Full Text] [PDF]    

Li Li, Patricia A. Thompson, and Richard L. Kitchens

Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors
J. Lipid Res. 2008 49: 1782-1793. First Published on May 22, 2008; doi:10.1194/jlr.M800172-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Kjell Stålberg, Andrea C. Neal, Hans Ronne, and Ulf Ståhl

Identification of a novel GPCAT activity and a new pathway for phosphatidylcholine biosynthesis in S. cerevisiae
J. Lipid Res. 2008 49: 1794-1806. First Published on April 22, 2008; doi:10.1194/jlr.M800129-JLR200 [Abstract] [Full Text] [PDF]    

Ju He, Rachel M. Haney, Mohsin Vora, Vladislav V. Verkhusha, Robert V. Stahelin, and Tatiana G. Kutateladze

Molecular mechanism of membrane targeting by the GRP1 PH domain^,
J. Lipid Res. 2008 49: 1807-1815. First Published on May 9, 2008; doi:10.1194/jlr.M800150-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Hao Li, Stephen D. Turley, Benny Liu, Joyce J. Repa, and John M. Dietschy

GM2/GD2 and GM3 gangliosides have no effect on cellular cholesterol pools or turnover in normal or NPC1 mice
J. Lipid Res. 2008 49: 1816-1828. First Published on April 30, 2008; doi:10.1194/jlr.M800180-JLR200 [Abstract] [Full Text] [PDF]    

Motohiro Sekiya, Jun-ichi Osuga, Naoya Yahagi, Hiroaki Okazaki, Yoshiaki Tamura, Masaki Igarashi, Satoru Takase, Kenji Harada, Sachiko Okazaki, Yoko Iizuka, Ken Ohashi, Hiroaki Yagyu, Mitsuyo Okazaki, Takanari Gotoda, Ryozo Nagai, Takashi Kadowaki, Hitoshi Shimano, Nobuhiro Yamada, and Shun Ishibashi

Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
J. Lipid Res. 2008 49: 1829-1838. First Published on May 14, 2008; doi:10.1194/jlr.M800198-JLR200 [Abstract] [Full Text] [PDF]    

Patient-Oriented and Epidemiological Research:

Jian Shen, Donna K. Arnett, Pablo Pérez-Martínez, Laurence D. Parnell, Chao-Qiang Lai, James M. Peacock, James E. Hixson, Michael Y. Tsai, Robert J. Straka, Paul N. Hopkins, and José M. Ordovás

The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN study^,
J. Lipid Res. 2008 49: 1839-1845. First Published on April 16, 2008; doi:10.1194/jlr.P700033-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Clive R. Pullinger, Bradley E. Aouizerat, Irina Movsesyan, Vincent Durlach, Eric J. Sijbrands, Katsuyuki Nakajima, Annie Poon, Geesje M. Dallinga-Thie, Hiroaki Hattori, Lauri L. Green, Pui-Yan Kwok, Richard J. Havel, Philip H. Frost, Mary J. Malloy, and John P. Kane

An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients
J. Lipid Res. 2008 49: 1846-1854. First Published on April 25, 2008; doi:10.1194/jlr.P800011-JLR200 [Abstract] [Full Text] [PDF] Supplemental Data    

Methods:

Osama Y. Al-Dirbashi, Tomofumi Santa, Mohamed S. Rashed, Zuhair Al-Hassnan, Nobuyuki Shimozawa, Aziza Chedrawi, Minnie Jacob, and Manhal Al-Mokhadab

Rapid UPLC-MS/MS method for routine analysis of plasma pristanic, phytanic, and very long chain fatty acid markers of peroxisomal disorders
J. Lipid Res. 2008 49: 1855-1862. First Published on April 25, 2008; doi:10.1194/jlr.D800019-JLR200 [Abstract] [Full Text] [PDF]    

Calendar:

Calendar
J. Lipid Res. 2008 49: 1863-1864. [Full Text] [PDF]    

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