x
Filter:
Filters applied
- Commentaries
- Tsimikas, SotiriosRemove Tsimikas, Sotirios filter
- Journal of Lipid ResearchRemove Journal of Lipid Research filter
JLR Commentaries
2 Results
- CommentaryOpen Access
In search of a physiological function of lipoprotein(a): causality of elevated Lp(a) levels and reduced incidence of type 2 diabetes
Journal of Lipid ResearchVol. 59Issue 5p741–744Published online: April 2, 2018- Sotirios Tsimikas
Cited in Scopus: 12“Shallow (wo)men believe in luck or in circumstance. Strong (wo)men believe in cause and effect.”(Ralph Waldo Emerson, The Conduct of Life, 1860). - CommentaryOpen Access
HDL-C, ABCA1-mediated cholesterol efflux, and lipoprotein(a): insights into a potential novel physiologic role of lipoprotein(a)
Journal of Lipid ResearchVol. 56Issue 7p1241–1244Published online: May 26, 2015- Calvin Yeang
- Sotirios Tsimikas
Cited in Scopus: 3Lipoprotein(a) [Lp(a)], an atherogenic lipoprotein consisting of apo(a) covalently bound to apo B-100 of LDL, is a prevalent genetic risk factor for cardiovascular disease. Several genome wide association studies have established an association between SNPs in LPA, the gene encoding apo(a), and coronary artery disease and myocardial infarction (MI) (1–3). Moreover, recent Mendelian randomization studies also demonstrate that LPA SNPs associated with elevated plasma Lp(a) levels also predict development of MI (4, 5) and aortic valve stenosis (6, 7), supporting a role for Lp(a) as a genetically determined, independent, causal risk factor for these diseases.
