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JLR Commentaries
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- CommentaryOpen Access
Genetic evidence for independent causal relationships between metabolic biomarkers and risk of coronary artery diseases
Journal of Lipid ResearchVol. 62100064Published online: March 7, 2021- Hooman Allayee
Cited in Scopus: 0Decades of epidemiological research have identified numerous risk factors and biomarkers that are associated with risk of coronary artery disease (CAD) and myocardial infarction. The most well recognized of these are circulating levels of total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides, as well as metabolic syndrome-related traits, such as obesity, hypertension, and T2D (1). However, the association of a biomarker with CAD in observational studies does not necessarily prove a causal relationship.
