May 2019

Volume 60Issue 5p911-1066
Open Access
COVER: Ceramide has been proposed to regulate diverse cellular processes by influencing membrane properties and by directly binding to effector proteins. Dysregulation of ceramide metabolism results in altered cellular responses and has been implicated in many diseases. Advances over the past decade have improved our understanding of ceramide as a bioactive lipid, with promise for development of therapeutic strategies to treat ceramide-regulated diseases. (See Stith et al., p. 913.)...
COVER: Ceramide has been proposed to regulate diverse cellular processes by influencing membrane properties and by directly binding to effector proteins. Dysregulation of ceramide metabolism results in altered cellular responses and has been implicated in many diseases. Advances over the past decade have improved our understanding of ceramide as a bioactive lipid, with promise for development of therapeutic strategies to treat ceramide-regulated diseases. (See Stith et al., p. 913.)

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