September 2018

Volume 59Issue 9p1549-1792
Open Access
COVER: Cisplatin treatment can result in apoptotic renal cell death, leading to changes in lipid distribution in the kidney. Cilastatin protects proximal tubule cells from cisplatin-induced apoptosis, practically restoring renal lipid distribution to control levels and recovering renal function. Therefore, lipid imaging helps visualize renal function status and can be a useful tool for assessing nephrotoxicants and novel nephroprotective therapies. (See Moreno-Gordaliza et al., p.1561.)...
COVER: Cisplatin treatment can result in apoptotic renal cell death, leading to changes in lipid distribution in the kidney. Cilastatin protects proximal tubule cells from cisplatin-induced apoptosis, practically restoring renal lipid distribution to control levels and recovering renal function. Therefore, lipid imaging helps visualize renal function status and can be a useful tool for assessing nephrotoxicants and novel nephroprotective therapies. (See Moreno-Gordaliza et al., p.1561.)

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