October 2014
Volume 55Issue 10p1983-2193
Open Access
COVER: Clearance of LDL is highly regulated via the LDL receptor pathway. Apolipoprotein
E clears atherogenic lipoproteins via the alternate receptors. Several copies of 28
residue apoE mimetic peptide consisting of 141-150 apoE receptor binding domain covalently
linked to the lipid associating peptide 18A (hE18A) bind to all of the atherogenic
lipoproteins and clear them from circulation rapidly via the heparan sulfate proteoglycans.
(See White et al., p. 2007.)...Show more
COVER: Clearance of LDL is highly regulated via the LDL receptor pathway. Apolipoprotein
E clears atherogenic lipoproteins via the alternate receptors. Several copies of 28
residue apoE mimetic peptide consisting of 141-150 apoE receptor binding domain covalently
linked to the lipid associating peptide 18A (hE18A) bind to all of the atherogenic
lipoproteins and clear them from circulation rapidly via the heparan sulfate proteoglycans.
(See White et al., p. 2007.)
