November 2012

Volume 53Issue 11p2253-2485
Open Access
COVER: Paraoxonase 1 (PON1) is an HDL-associated antioxidant enzyme with broad substrate specificity and strong associations to numerous human diseases. This figure illustrates the percentage of PON1 enzyme activity that is attributable to dietary (bolded) and genetic factors identified in our study utilizing regression methods, in decreasing order of magnitude. The associations of dietary cholesterol, iron in non-anemic patients, and folic acid are, to the best of the authors' knowledge, novel, while we also confirm past reports of vitamin C and alcohol use on PON1 activity. (See Kim et al. p. 2450.)...
COVER: Paraoxonase 1 (PON1) is an HDL-associated antioxidant enzyme with broad substrate specificity and strong associations to numerous human diseases. This figure illustrates the percentage of PON1 enzyme activity that is attributable to dietary (bolded) and genetic factors identified in our study utilizing regression methods, in decreasing order of magnitude. The associations of dietary cholesterol, iron in non-anemic patients, and folic acid are, to the best of the authors' knowledge, novel, while we also confirm past reports of vitamin C and alcohol use on PON1 activity. (See Kim et al. p. 2450.)

Commentary

Research Articles

Patient-Oriented and Epidemiological Research

Methods

Advertisement