JLR Patient-Oriented and Epidemiological Research

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  • Patient-Oriented and Epidemiological Research
    Open Access

    Associations between intensive diabetes therapy and NMR-determined lipoprotein subclass profiles in type 1 diabetes

    Journal of Lipid Research
    Vol. 57Issue 2p310–317Published online: December 9, 2015
    • Ying Zhang
    • Alicia J. Jenkins
    • Arpita Basu
    • Julie A. Stoner
    • Maria F. Lopes-Virella
    • Richard L. Klein
    • and others
    Cited in Scopus: 12
      Our objective is to define differences in circulating lipoprotein subclasses between intensive versus conventional management of type 1 diabetes during the randomization phase of the Diabetes Control and Complications Trial (DCCT). NMR-determined lipoprotein subclass profiles (NMR-LSPs), which estimate molar subclass concentrations and mean particle diameters, were determined in 1,294 DCCT subjects after a median of 5 years (interquartile range: 4–6 years) of randomization to intensive or conventional diabetes management.

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    ISSN 0022-2275
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