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Journal of Lipid Research
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    • Patient-Oriented and Epidemiological Research
      Open Access

      Serum lipoprotein (a) concentrations are inversely associated with T2D, prediabetes, and insulin resistance in a middle-aged and elderly Chinese population

      Journal of Lipid Research
      Vol. 56Issue 4p920–926Published online: January 3, 2015
      • Lin Ding
      • An Song
      • Meng Dai
      • Min Xu
      • Wanwan Sun
      • Baihui Xu
      • and others
      Cited in Scopus: 45
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        Lipoprotein (a) [Lp(a)], an LDL-like particle, has been proposed as a causal risk factor for CVD among general populations. Meanwhile, both serum Lp(a) and diabetes increase the risk of CVD. However, the relationship between serum Lp(a) and T2D is poorly characterized, especially in the Asian population. Therefore, we conducted a cross-sectional study in 10,122 participants aged 40 years or older in Jiading District, Shanghai, China. Our study found that the prevalence of T2D was decreased from 20.9% to 15.0% from the lowest quartile to the highest quartile of serum Lp(a) concentrations (P for trend <0.0001).
        Serum lipoprotein (a) concentrations are inversely associated with T2D, prediabetes, and insulin resistance in a middle-aged and elderly Chinese population[S]
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