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JLR Patient-Oriented and Epidemiological Research
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- Patient-Oriented and Epidemiological ResearchOpen Access
Omental adipocyte hypertrophy relates to coenzyme Q10 redox state and lipid peroxidation in obese women
Journal of Lipid ResearchVol. 56Issue 10p1985–1992Published online: August 3, 2015- Thomas Grenier-Larouche
- Anne Galinier
- Louis Casteilla
- André C. Carpentier
- André Tchernof
Cited in Scopus: 12Occurrence of oxidative stress in white adipose tissues contributes to its dysfunction and the development of obesity-related metabolic complications. Coenzyme Q10 (CoQ10) is the single lipophilic antioxidant synthesized in humans and is essential for electron transport during mitochondrial respiration. To understand the role of CoQ10 in adipose tissue physiology and dysfunction, the abundance of the oxidized and reduced (CoQ10red) isoforms of the CoQ10 were quantified in subcutaneous and omental adipose tissues of women covering the full range of BMI (from 21.5 to 53.2 kg/m2).