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- Research ArticleOpen Access
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men
Journal of Lipid ResearchVol. 63Issue 10100269Published online: August 28, 2022- Chloé Rauzier
- Benoît Lamarche
- André J. Tremblay
- Patrick Couture
- Frédéric Picard
Cited in Scopus: 0Low circulating concentrations of insulin-like growth factor binding protein-2 (IGFBP-2) have been associated with dyslipidemia, notably with high triglyceride (TG) levels. However, the determinants by which IGFBP-2 influences lipoprotein metabolism, especially that of TG-rich lipoproteins (TRLs), are poorly understood. Here, we aimed to assess the relationships between IGFBP-2 levels and lipoprotein production and catabolism in human subjects. Fasting IGFBP-2 concentrations were measured in the plasma of 219 men pooled from previous lipoprotein kinetics studies.