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Journal of Lipid Research
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    • Research Article
      Open Access

      Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men

      Journal of Lipid Research
      Vol. 63Issue 10100269Published online: August 28, 2022
      • Chloé Rauzier
      • Benoît Lamarche
      • André J. Tremblay
      • Patrick Couture
      • Frédéric Picard
      Cited in Scopus: 0
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        Low circulating concentrations of insulin-like growth factor binding protein-2 (IGFBP-2) have been associated with dyslipidemia, notably with high triglyceride (TG) levels. However, the determinants by which IGFBP-2 influences lipoprotein metabolism, especially that of TG-rich lipoproteins (TRLs), are poorly understood. Here, we aimed to assess the relationships between IGFBP-2 levels and lipoprotein production and catabolism in human subjects. Fasting IGFBP-2 concentrations were measured in the plasma of 219 men pooled from previous lipoprotein kinetics studies.
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