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Regular Research Articles
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- Research ArticleOpen Access
Associations of HDL metrics with coronary artery calcium score and density among women traversing menopause
Journal of Lipid ResearchVol. 62100098Published online: July 22, 2021- Samar R. El Khoudary
- Alexis Nasr
- Karen A. Matthews
- Trevor J. Orchard
- Maria M. Brooks
- Jeffrey Billheimer
- and others
Cited in Scopus: 0The cardioprotective association of high-density lipoprotein cholesterol (HDL-C) may vary by menopause stage or estradiol level. We tested whether associations of comprehensive HDL metrics (HDL subclasses, phospholipid and triglyceride content, and HDL cholesterol efflux capacity [HDL-CEC]) with coronary artery calcium (CAC) score and density vary by menopause stage or estradiol level in women transitioning through menopause. Participants (N = 294; mean age [SD]: 51.3 [2.9]) had data on HDL metrics and CAC measures at one or two time points during the menopause transition.